Endocrine Abstracts

Introduction: Secondary osteoporosis is defined as bone loss caused or exacerbated by other clinical disorders. Secondary osteoporosis can be due to a wide range of medical disorders, including endocrine disorders and genetic disorders. We are presenting a clinical case which the patient diagnosed as acute intermittent porphyria while being investigated for secondary osteoporosis.Clinical Case: 41-year-old female patient applied with bone and back pain, ...

Diabetes is one of the risk factors for Achilles tendon rupture. Tendon thickening and impaired collagen organization have been reported in diabetic patients in small studies. In this report, we present the rupture of the Achilles tendon in a female patient with poorly controlled diabetes mellitus and diabetic neuropathy. A 52-years-old woman with a medical history of diabetes treated by intensive insulin therapy, developed pain in the right heel without previous trauma. The p...

İntroduction: Gitelman syndrome is characterized with hypokalemia, hypomagnesemia, hypocalciuria, metabolic alkalosis and neurological symptoms like muscle weakness. The association of GS and type 1 diabetes is rare, only described in a few case reports. We report a patient with unusual combination of Gitelman syndrome, Type 1 Diabetes Mellitus whose presentation was erytrocytosis.Case: A 26-year old male was diagnosed as Gitelman’s syndrome 5...

A 44-year-old man with 6 months history of headache, fatique, depressive mood, anorexia, impotence, decreased libido, poliuria and polidypsia. The results of the physical examination were normal, except the patient had noduler guatr. Baseline hormonal investigations and dinamic tests showed panhypopituitarism and partial central diabetes insipidus. Magnetic resonance imaging (MRI) of the pituitary gland showed enlarged pituitary gland and a marked thickening (4.5 mm) of the in...

Subacute thyroiditis is a painful disease of the thyroid gland characterized with granulomatous inflammation. Adalimumab is a human monoclonal anti TNF antibody used in the treatment of several autoimmune diseases. Here we report a case of subacute thyroiditis associated with adalimumab treatment for ankylosing spondylitis. A 42 year old female patient was admitted to the hospital for fever, chills and neck pain radiating to the right ear. She was diagnosed with ankylosing spo...

Riedel thyroiditis (RT) is a rarest form of thyroiditis, and characterized by dense fibrosis of the throid gland and infiltration into surrounding tissues. RT generally presents with local symptoms association with compression and also fibrotic process can impact thyroid and parathyroid functions. We report a case with RT which presents with compression findings and also hypoparathyroidism and hypothyroidism. 30 year old women visited our outpatient clinic with a complaint of ...

Insulinomas are rare neuroendocrine tumors (NETs) of the pancreas with an incidence of four per 1 million persons per year. The co-existence of diabetes mellitus (DM) and insulinoma is very rare. We report a case of 73 year old women with malignant insulinoma and type 2 DM. A 73 year old woman with type 2 diabetes was referred to our clinic for recurrent and severe hypoglycemia especially in the early morning hours. The patient had a history of type 2 DM for 10 years. Although...

Introduction: Ornithine transcarbamylase deficiency (OTCD) is a urea cycle disorder that causes the accumulation of ammonia, which can lead to neurocognitive problems in patients1. Here we report a 21-year-old man who was diagnosed with OTCD during investigation for secondary osteoporosis.Case: The patient applied to the Endocrinology department complaining of widespread muscle-joint pain, shortening in height, nausea/vomiting attacks followed...

Although adrenal gland involvement may be seen in patients with diffuse (non-Hodgkin) lymphoma, primary adrenal lymphoma is quite rare and adrenal insufficiency accompanies the clinical picture in 2/3 of cases.Case: A 70-year-old male patient presenting with anorexia and weight loss was referred to our clinic for bilateral adrenal masses, which were detected by abdominal computerized tomography (CT) as 5.2×5.2×2.7 cm in the right adrenal and 11...

A 49-year-old man with history of nodular goitre operation was referred to our clinic because of MTC in postoperative pathology. He had hypertension, postoperative hypothyroidism, no family history of thyroid carcinoma and sudden death. Laboratuary investigations showed high level of calcitonin (C) (763 pg/ml; normal<150), Carcino embryogenic antigen (CEA) (175 ng/ml; normal<2.5), normal thyroid function tests, parathormone, urinary catecholamines. Ser904 polymorphism ...